Tutorials and General Instruction – Arranged from Beginner to Advanced, more or less.
The Human Brain
From the Franklin Institute, this has to be one of the best on our subject and is particularly directed at the beginning student. It is also one of the best designed sites on the web.
BBC The Human Body and Mind
This BBC site covers body and mind as well as several additional systems.
The Brain from Top to Bottom
Based at McGill University, this Canadian site is a wonder. With plenty of colored illustrations, it discusses a dozen or more specific areas of the brain at three different levels (beginner, medium, advanced). Go through the three one by one and in a week you will be an expert.
Brain Atlas
An extremely well-linked site from the Lundbeck Institute, this one makes an excellent pair with the above.
NIH Parkinson’s Disease Planning Workshop
An NIH attempt to do what we are attempting to do – get cross-talk between the disciplines. Good general guide.
Medline Plus
Pretty much the “party line” but good quality and a lot of it. Good place to begin if you keep your mind open once you are done.
Microbiology
A great presentation on the stuff you forgot in introductory Micro by Dr. Gary Kaiser.
Cell Biology
University of Texas Medical School tutorial for beginning to intermediate.
Basic and Clinical Neuroscience
This Columbia University-based medium to advanced site offers approximately 40 lectures representing their annual symposium’s presenters. Each talk is available in printed or recorded form.
Neuroscience
A mid-level neuroscience tutorial from the Washington University School of Medicine.
NIH Videos
NIH Portal – video is just part of it.
E-Medicine
Advanced. Definitely advanced.
About Parkinson’s Disease
Parkinson’s Disease was described 200 years ago by Dr. James Parkinson of London, England. Despite two centuries of research it is still a great unknown. We have been unable to define cause, course, or cure. Although virtually unknown in history it is more common than ever today and claims even younger victims.
Thus, the question of just what is PD has no clear answer. Everyone has an opinion with evidence to back it up and I am no exception. The following model forms the foundation of this site:
PD has no single cause and, instead, results from a preponderance of causal factors of varying importance. It is not necessary that all factors be present, simply that enough of them be encountered that their combined weights be enough to trigger a set of degenerative processes that lead to the condition we call PD.
PD is not a neurological disease. It is actually a combination of immune and endocrine problems that damage the central nervous system. The neurological symptoms are just that, symptoms. The primary driving forces come from the immune and endocrine systems.
While genetics plays a small role, epigenetics plays a larger one. Events even prior to conception have an impact in that they influence the maternal stress circuits which, in turn, impact the fetal endocrine system.
Fetal immune challenge by maternal infection plays the largest role as it further disrupts the endocrine system, primes the fetal immune system to trigger an autotoxic reaction to future infection, and results in reduced neuronal density in the substantia nigra.
About PD
Tutorials and General Instruction – Arranged from Beginner to Advanced, more or less.
The Human Brain
From the Franklin Institute, this has to be one of the best on our subject and is particularly directed at the beginning student. It is also one of the best designed sites on the web.
BBC The Human Body and Mind
This BBC site covers body and mind as well as several additional systems.
The Brain from Top to Bottom
Based at McGill University, this Canadian site is a wonder. With plenty of colored illustrations, it discusses a dozen or more specific areas of the brain at three different levels (beginner, medium, advanced). Go through the three one by one and in a week you will be an expert.
Brain Atlas
An extremely well-linked site from the Lundbeck Institute, this one makes an excellent pair with the above.
NIH Parkinson’s Disease Planning Workshop
An NIH attempt to do what we are attempting to do – get cross-talk between the disciplines. Good general guide.
Medline Plus
Pretty much the “party line” but good quality and a lot of it. Good place to begin if you keep your mind open once you are done.
Microbiology
A great presentation on the stuff you forgot in introductory Micro by Dr. Gary Kaiser.
Cell Biology
University of Texas Medical School tutorial for beginning to intermediate.
Basic and Clinical Neuroscience
This Columbia University-based medium to advanced site offers approximately 40 lectures representing their annual symposium’s presenters. Each talk is available in printed or recorded form.
Neuroscience
A mid-level neuroscience tutorial from the Washington University School of Medicine.
NIH Videos
NIH Portal – video is just part of it.
E-Medicine
Advanced. Definitely advanced.
About Parkinson’s Disease
Parkinson’s Disease was described 200 years ago by Dr. James Parkinson of London, England. Despite two centuries of research it is still a great unknown. We have been unable to define cause, course, or cure. Although virtually unknown in history it is more common than ever today and claims even younger victims.
Thus, the question of just what is PD has no clear answer. Everyone has an opinion with evidence to back it up and I am no exception. The following model forms the foundation of this site:
PD has no single cause and, instead, results from a preponderance of causal factors of varying importance. It is not necessary that all factors be present, simply that enough of them be encountered that their combined weights be enough to trigger a set of degenerative processes that lead to the condition we call PD.
PD is not a neurological disease. It is actually a combination of immune and endocrine problems that damage the central nervous system. The neurological symptoms are just that, symptoms. The primary driving forces come from the immune and endocrine systems.
While genetics plays a small role, epigenetics plays a larger one. Events even prior to conception have an impact in that they influence the maternal stress circuits which, in turn, impact the fetal endocrine system.
Fetal immune challenge by maternal infection plays the largest role as it further disrupts the endocrine system, primes the fetal immune system to trigger an autotoxic reaction to future infection, and results in reduced neuronal density in the substantia nigra.