Comments for A Matter of Balance http://parkinsonsonline.org/blog1 A Dance With Parkinsons Disease Tue, 27 Jul 2010 13:16:54 +0000 hourly 1 http://wordpress.org/?v=3.0 Comment on Factsheet: Helicobacter pylori by Rick http://parkinsonsonline.org/blog1/?p=635&cpage=1#comment-241 Rick Tue, 27 Jul 2010 13:16:54 +0000 http://parkinsonsonline.org/blog1/?p=635#comment-241 H. pylori is a fascinating little beast. It comes in a variety of strains which range from relatively harmless to downright nasty when provoked. It is the only creature known to inhabit the human stomach and the human GI tract is the only home that it has. It is hard to believe that this is simply a host and parasite relationship. Somewhere I read recently that an HP infection conferred a degree of immunity to TB, of all things! If so, then there may be other such benefits that we are unaware of. That, in turn, would provide a very tidy explanation for its high rate in developing countries. It could be a major factor in survival under those conditions. Thanks for the comment! H. pylori is a fascinating little beast. It comes in a variety of strains which range from relatively harmless to downright nasty when provoked. It is the only creature known to inhabit the human stomach and the human GI tract is the only home that it has. It is hard to believe that this is simply a host and parasite relationship.

Somewhere I read recently that an HP infection conferred a degree of immunity to TB, of all things! If so, then there may be other such benefits that we are unaware of. That, in turn, would provide a very tidy explanation for its high rate in developing countries. It could be a major factor in survival under those conditions. Thanks for the comment!

]]> Comment on Factsheet: Helicobacter pylori by helicobacter pylori http://parkinsonsonline.org/blog1/?p=635&cpage=1#comment-240 helicobacter pylori Tue, 27 Jul 2010 06:35:44 +0000 http://parkinsonsonline.org/blog1/?p=635#comment-240 Helicobacter pylori infection is present in 30 to 50 percent of the world’s population. The Helicobacter pylori infection rate is higher in developing countries, most likely due to poor sanitary conditions. H. pylori infection still affects tens of millions in the United States, where H. pylori prevalence is estimated between 10-20% of the population. Helicobacter pylori infection is present in 30 to 50 percent of the world’s population. The Helicobacter pylori infection rate is higher in developing countries, most likely due to poor sanitary conditions. H. pylori infection still affects tens of millions in the United States, where H. pylori prevalence is estimated between 10-20% of the population.

]]> Comment on YOPD – Evidence for Early Life Origins (Part 1) by Rick http://parkinsonsonline.org/blog1/?p=336&cpage=1#comment-28 Rick Tue, 01 Dec 2009 18:29:42 +0000 http://parkinsonsonline.org/blog1/?p=336#comment-28 Robert- Thank you for the kind words and, yes, I did get your mail. I hope that the DXM keeps you stable right on along. Feel free to "pick" at anything I post, by the way. If these theories ever do get noticed, it would be good if they had been stress-tested in advance. -Rick Robert-
Thank you for the kind words and, yes, I did get your mail. I hope that the DXM keeps you stable right on along. Feel free to “pick” at anything I post, by the way. If these theories ever do get noticed, it would be good if they had been stress-tested in advance.
-Rick

]]> Comment on YOPD – Evidence for Early Life Origins (Part 1) by Robert Smith http://parkinsonsonline.org/blog1/?p=336&cpage=1#comment-27 Robert Smith Tue, 01 Dec 2009 17:54:28 +0000 http://parkinsonsonline.org/blog1/?p=336#comment-27 This is the first time I have logged on to your blog. This is outstanding work! Keep it up. Did you get my reply to your email? I'm still taking only the bedtime 4mg dose of DXM. Dyskinesia and freezing are not problems for me at this point, but it's good to know about the possible benefits of daytime dosing if/when they appear. Robert This is the first time I have logged on to your blog. This is outstanding work! Keep it up.
Did you get my reply to your email?
I’m still taking only the bedtime 4mg dose of DXM. Dyskinesia and freezing are not problems for me at this point, but it’s good to know about the possible benefits of daytime dosing if/when they appear.
Robert

]]> Comment on PD and Alzheimer’s: A Critical Difference by paula http://parkinsonsonline.org/blog1/?p=243&cpage=1#comment-26 paula Sun, 29 Nov 2009 22:43:54 +0000 http://parkinsonsonline.org/blog1/?p=243#comment-26 Through personal experience, it should not be assumed that people with pd need acetycholine as alzheimers patients do. I was prescribed aricept and it increased my already abundant acetycholine so high that i was so weak i felt almost paralyzed. Doctors do not know about the critical need to not have too much acetycholine when our dopamine is low. Bad news...dangerous for me. i think it could kill someone. pauoa Through personal experience, it should not be assumed that people with pd need acetycholine as alzheimers patients do. I was prescribed
aricept and it increased my already abundant acetycholine so high that i was so weak i felt almost paralyzed.

Doctors do not know about the critical need to not have too much acetycholine when our dopamine is low.

Bad news…dangerous for me. i think it could kill someone.

pauoa

]]> Comment on YOPD – Evidence for Early Life Origins (Part 1) by paula http://parkinsonsonline.org/blog1/?p=336&cpage=1#comment-25 paula Sun, 29 Nov 2009 22:25:28 +0000 http://parkinsonsonline.org/blog1/?p=336#comment-25 thought you would never pull it all together. but you did and your timing is outstanding. great work! paula thought you would never pull it all together. but you did and your timing is outstanding.

great work!
paula

]]> Comment on An Experience with Wheat Gluten by Rick http://parkinsonsonline.org/blog1/?p=89&cpage=1#comment-23 Rick Sun, 15 Nov 2009 15:46:32 +0000 http://parkinsonsonline.org/blog1/?p=89#comment-23 Purportedly, the harmful reaction does carry over into the beer. In fact, you can purchase "gluten-free" beers intended for those who deal with celiac disease. I would suspect that, in this case, that more damage would be done by the alcohol itself. I see at least two possibilities. One is the ever-present "wild card" of genetics and the other is an acquired reaction as a result of gastric inflammation producing a "leaky gut" scenario. The first would tie in with the idea that as the major groups of our ancestors moved out of Africa, those that moved in various directions evolved differently in response to their technology. Those who ended up in the Middle East evolved to take advantage of their agriculture and their descendants tolerate grains the best. Others ended up on the Asian steppes and evolved to take advantage of the availability of milk. My ancestors, on the other hand, ended up in Europe painting their naked butts blue. As a result, hypothetically, caucasians have higher rates of PD. The second arises from the fact that inflammation increases the permeability of the gut which, in turn, allows the partially digested proteins of the grain to come into contact with the immune system which, then, mounts a defense. Like all proposed causes, neither of these make sense by themselves, but both of them fit nicely into the neuroinflammatory model. Inflammation opens up a dozen vulnerabiliies and their sum is PD. Purportedly, the harmful reaction does carry over into the beer. In fact, you can purchase “gluten-free” beers intended for those who deal with celiac disease. I would suspect that, in this case, that more damage would be done by the alcohol itself. I see at least two possibilities. One is the ever-present “wild card” of genetics and the other is an acquired reaction as a result of gastric inflammation producing a “leaky gut” scenario.

The first would tie in with the idea that as the major groups of our ancestors moved out of Africa, those that moved in various directions evolved differently in response to their technology. Those who ended up in the Middle East evolved to take advantage of their agriculture and their descendants tolerate grains the best. Others ended up on the Asian steppes and evolved to take advantage of the availability of milk. My ancestors, on the other hand, ended up in Europe painting their naked butts blue. As a result, hypothetically, caucasians have higher rates of PD.

The second arises from the fact that inflammation increases the permeability of the gut which, in turn, allows the partially digested proteins of the grain to come into contact with the immune system which, then, mounts a defense.

Like all proposed causes, neither of these make sense by themselves, but both of them fit nicely into the neuroinflammatory model. Inflammation opens up a dozen vulnerabiliies and their sum is PD.

]]> Comment on An Experience with Wheat Gluten by Rogerstar1 http://parkinsonsonline.org/blog1/?p=89&cpage=1#comment-22 Rogerstar1 Sun, 15 Nov 2009 13:38:38 +0000 http://parkinsonsonline.org/blog1/?p=89#comment-22 Interesting. I've wondered if excessive beer drnking and the ingestion of grains thereby might have be a contributing factor. Mike Fox hasn't come right out and said it but did remark in an early book he authored that he drank way too much beer ...hops = grains. To the point of nightly stupefication. Interesting. I’ve wondered if excessive beer drnking and the ingestion of grains thereby might have be a contributing factor. Mike Fox hasn’t come right out and said it but did remark in an early book he authored that he drank way too much beer …hops = grains. To the point of nightly stupefication.

]]> Comment on An Experience with Wheat Gluten by Rick http://parkinsonsonline.org/blog1/?p=89&cpage=1#comment-21 Rick Sat, 14 Nov 2009 20:02:39 +0000 http://parkinsonsonline.org/blog1/?p=89#comment-21 If you haven't already done so, read over the category on neuroinflammation. There are a lot of the answers there. Once your immune system is activated, another infection (cholera, for example) just makes it worse. And while I haven't elaborated on it yet, the endocrine system's involvement in Young Onset provides clues to the anxiety. If you haven’t already done so, read over the category on neuroinflammation. There are a lot of the answers there. Once your immune system is activated, another infection (cholera, for example) just makes it worse. And while I haven’t elaborated on it yet, the endocrine system’s involvement in Young Onset provides clues to the anxiety.

]]> Comment on An Experience with Wheat Gluten by netgypsy http://parkinsonsonline.org/blog1/?p=89&cpage=1#comment-20 netgypsy Sat, 14 Nov 2009 06:02:18 +0000 http://parkinsonsonline.org/blog1/?p=89#comment-20 Really interesting. It would appear that any of those could ba A culprit because I don't think there is just ONE. But there may be. Who knows right now. Molds exist in other grass type feed products and in most everything. The toxin in fescue causes photosensitivity, overly long gestation periods, spontaneous abortion, lack of milk production, "red bag" births and other nasty things in horses and cattle. I can see them triggering something like PD PD is so common there almost has to be an environmental facet although different triggers certainly could cause vulnerable individuals to become overly sensitive to certain toxins or viruses or food products. I would hope something simple can at least control it better than is being done today since the end result is pretty much similar in all PD sufferers with the positive response to dopamine. I also believe there is definitely a genetic component but look at diabetes and what a killer it was before it was at least determined how to deal with it. We just haven't quite put the pieces together correctly. I've had three different autoimmune problems before I developed symptoms of PD and right before I developed what I considered to be the first symptoms - anxiety attacks and depression - I had a horrendous illness. Almost like what you read about as the symptoms of cholera. I was in another country when I developed it and it took more than a month to get over it. I wonder to this day if that illness was the trigger that started some type of autoimmune reaction in my brain in my particular case and made me vulnerable to any number of other triggers. But the very fact that this problem is generally progressive is an indication that something continues to cause damage to those who have been somehow rendered more sensitive or vulnerable. It would be interesting if it weren't so darned annoying to say it mildly. Really interesting. It would appear that any of those could ba A culprit because I don’t think there is just ONE. But there may be. Who knows right now.

Molds exist in other grass type feed products and in most everything.

The toxin in fescue causes photosensitivity, overly long gestation periods, spontaneous abortion, lack of milk production, “red bag” births and other nasty things in horses and cattle.

I can see them triggering something like PD

PD is so common there almost has to be an environmental facet although different triggers certainly could cause vulnerable individuals to become overly sensitive to certain toxins or viruses or food products.

I would hope something simple can at least control it better than is being done today since the end result is pretty much similar in all PD sufferers with the positive response to dopamine.

I also believe there is definitely a genetic component but look at diabetes and what a killer it was before it was at least determined how to deal with it. We just haven’t quite put the pieces together correctly.

I’ve had three different autoimmune problems before I developed symptoms of PD and right before I developed what I considered to be the first symptoms – anxiety attacks and depression – I had a horrendous illness. Almost like what you read about as the symptoms of cholera. I was in another country when I developed it and it took more than a month to get over it. I wonder to this day if that illness was the trigger that started some type of autoimmune reaction in my brain in my particular case and made me vulnerable to any number of other triggers.

But the very fact that this problem is generally progressive is an indication that something continues to cause damage to those who have been somehow rendered more sensitive or vulnerable.

It would be interesting if it weren’t so darned annoying to say it mildly.

]]>