<The immune and endocrine systems interact through the HPA axis.> 1: Baillieres Best Pract Res Clin Endocrinol Metab. 1999 Dec;13(4):555-65. Chronic inflammatory stress. Harbuz MS. University Research Centre for Neuroendocrinology, University of Bristol, UK. A major mechanism involved in maintaining homeostasis in response to chronic inflammation is the hypothalamo-pituitary-adrenal (HPA) axis, resulting in the release [...]
<Subsonics are inaudible, extremely low frequency, yet very powerful sound waves. In nature they almost always are linked to danger and thus trigger the fight or flight response. They are also quite rare. However, in the world of the Industrial Revolution they became steadily more common. Today, millions of us live with them. Only a [...]
February 17, 2010 – 12:33 pm
PD is a complex creature and difficult to understand. One way to overcome this problem is by using analogies to make it comprehensible. If a picture is worth a thousand words, then a good analogy is just as valuable. One major feature of YOPD is the struggle to maintain homeostasis, or balance, in the mind [...]
February 12, 2010 – 3:50 pm
Tutorials and General Instruction – Arranged from Beginner to Advanced, more or less. The Human Brain From the Franklin Institute, this has to be one of the best on our subject and is particularly directed at the beginning student. It is also one of the best designed sites on the web. BBC The Human Body [...]
By Rick
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Also posted in Cascade, Causes, Commentary, Immune System, Inflammation, Microglia, Nervous System, Neuroinflammation, Rants and Raves, Stress Response, Systems and PD, The Big Picture, Uncategorized
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February 8, 2010 – 12:12 pm
(This post references the graphic entitled “The Parkinson’s Cascade” found here.) Just as Young Onset Parkinson’s Disease can have a part of its origin in fetal exposure to maternal stress, so too does it arise from a similar exposure to problems with “Maternal Health” and particularly the products of maternal infection. Like the exposure to [...]
By Rick
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Also posted in Cascade, Causes, Environment, Immune System, Inflammation, Lipopolysaccharide (LPS), Microglia, Nervous System, Neuroinflammation, Processes, Uncategorized
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January 17, 2010 – 1:47 am
(The following post references the chart called “The Parkinson’s Cascade” which can be viewed here.) This is one of a series of attempts to explain my view of Parkinson’s Disease in hopes of stimulating research into new areas. I freely admit to errors in this work and hope that those will be brought to my [...]
By Rick
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Also posted in Cascade, Causes, Effects, Environment, Evidence, Neuroinflammation, Processes, Stress Response, Systems and PD, The Big Picture, Uncategorized, Young Onset PD
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Tagged Cascade, End
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December 29, 2009 – 7:11 pm
A report in this morning’s Science Daily News started a cascade of its own as several pieces of the puzzle clicked into place. With the charming title of “Seeing Family for the Holidays? Scientists Discover How the Stress Might Kill You” It goes on to state “”…. researchers from the University of Connecticut Health Center [...]
And What a Long, Strange Trip It’s Been
<Subsonics are inaudible, extremely low frequency, yet very powerful sound waves. In nature they almost always are linked to danger and thus trigger the fight or flight response. They are also quite rare. However, in the world of the Industrial Revolution they became steadily more common. Today, millions of us live with them. Only a [...]