<Note: The nature of wheat changed greatly with the Industrial Revolution as local varieties were replaced by standardized ones.> 1: Ann N Y Acad Sci. 2005 Jun;1051:787-98. Involvement of innate immunity in the development of inflammatory and autoimmune diseases. Tlaskalová-Hogenová H, Tucková L, Stepánková R, Hudcovic T, Palová-Jelínková L, Kozáková H, Rossmann P, Sanchez D, [...]
By Rick
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Also posted in Abstracts, Causes, Gastrointestinal System, History of PD, Immune System, Inflammation, Living With PD, Microglia, Neuroinflammation, Processes, Uncategorized, Wheat Gluten
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February 20, 2010 – 2:35 pm
I want to speculate a little more than I normally would, mainly because I haven’t finished researching this topic yet. I have been thinking about wheat, of course, and that has led to some interesting questions. What if our food is trying to kill us? I don’t mean that our poor choices of fatty snacks [...]
February 17, 2010 – 12:33 pm
PD is a complex creature and difficult to understand. One way to overcome this problem is by using analogies to make it comprehensible. If a picture is worth a thousand words, then a good analogy is just as valuable. One major feature of YOPD is the struggle to maintain homeostasis, or balance, in the mind [...]
February 12, 2010 – 3:50 pm
Tutorials and General Instruction – Arranged from Beginner to Advanced, more or less. The Human Brain From the Franklin Institute, this has to be one of the best on our subject and is particularly directed at the beginning student. It is also one of the best designed sites on the web. BBC The Human Body [...]
By Rick
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Also posted in Causes, Commentary, Endocrine System, Immune System, Inflammation, Microglia, Nervous System, Neuroinflammation, Rants and Raves, Stress Response, Systems and PD, The Big Picture, Uncategorized
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February 8, 2010 – 12:12 pm
(This post references the graphic entitled “The Parkinson’s Cascade” found here.) Just as Young Onset Parkinson’s Disease can have a part of its origin in fetal exposure to maternal stress, so too does it arise from a similar exposure to problems with “Maternal Health” and particularly the products of maternal infection. Like the exposure to [...]
By Rick
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Also posted in Causes, Endocrine System, Environment, Immune System, Inflammation, Lipopolysaccharide (LPS), Microglia, Nervous System, Neuroinflammation, Processes, Uncategorized
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January 17, 2010 – 1:47 am
(The following post references the chart called “The Parkinson’s Cascade” which can be viewed here.) This is one of a series of attempts to explain my view of Parkinson’s Disease in hopes of stimulating research into new areas. I freely admit to errors in this work and hope that those will be brought to my [...]
By Rick
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Also posted in Causes, Effects, Endocrine System, Environment, Evidence, Neuroinflammation, Processes, Stress Response, Systems and PD, The Big Picture, Uncategorized, Young Onset PD
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Tagged Cascade, End
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January 15, 2010 – 6:53 pm
A case can be made for each of the factors on the chart below as either causing or influencing PD. In coming posts, this “Cascade” will be discussed section by section.
September 15, 2009 – 7:45 pm
Over the last few weeks it has been somewhat like the clouds have parted and a new understanding of Parkinson’s Disease has emerged. While a great deal of research on the role of inflammation has long been available, it has been one of a number of possible explanations. It has now moved from the “possible” [...]
September 8, 2009 – 10:11 pm
Today’s London “Telegraph” reported on a study in the current issue of the journal “Neurology” that pretty much seals the case for neuroinflammation as causal in both Alzheimer’s and Parkinson’s Diseases. Beginning with a group of 222 AD patients with an average age of 83, they obtained baseline data via blood work and cognitive testing. [...]
August 28, 2009 – 6:49 pm
Activated microglia resemble armed sentries patrolling the perimeter of some ancient fortification. Walking along the top of the city wall in the darkness, they move quietly and with little fanfare so long as they detect no enemies. However, if they come upon an invader clambering over the parapet, the change is remarkable and instantaneous. There [...]
About PD
Tutorials and General Instruction – Arranged from Beginner to Advanced, more or less. The Human Brain From the Franklin Institute, this has to be one of the best on our subject and is particularly directed at the beginning student. It is also one of the best designed sites on the web. BBC The Human Body [...]